How much nicotine is in one hit of a vape?

The amount of nicotine ingested by taking a puff from an e-cigarette (often referred to as "one puff") does not have a fixed answer. This entirely depends on the type of e-cigarette, the concentration of the e-liquid, and your method of inhalation. However, I can provide you with a detailed calculation framework and common reference ranges.
?? Key Determining Factors and Theoretical Calculations
The nicotine content of a single puff mainly depends on the following two key factors:
The nicotine concentration of the e-liquid: It is usually indicated in milligrams per milliliter (mg/mL) or as a percentage (%). The higher the concentration, the greater the amount consumed per puff. For example, common concentrations include 3mg/mL, 6mg/mL, 20mg/mL, or 5% (which is 50mg/mL).
The atomization efficiency of the equipment (power and smoke volume): For devices with high power and large smoke volume (such as the Yaeom atomizer), the amount of e-liquid consumed per puff is much higher than that of the small power, refillable electronic cigarettes. A simple formula can help you estimate:
The nicotine intake per puff (mg) ≈ The amount of e-liquid consumed per puff (ml) × E-liquid concentration (mg/mL)
*Example: If you are using a common electronic cigarette device, each puff consumes approximately 0.05 ml of e-liquid. Using 20 mg/mL (i.e., 2%) e-liquid, then the theoretical intake per puff is approximately 0.05 ml × 20 mg = 1 mg of nicotine.*
?? Comparison of Different Product Types
To facilitate your understanding, we have compared the situations of three mainstream product types:
Product Type Typical Nicotine Concentration Range Estimated Intake per Mouth (Theoretical Value) Explanation and Common Product Examples
Single-use/Refillable Small Cigarettes Common: 20mg/mL (2%) to 50mg/mL (5%) of nicotine salts. Approximately 0.5 - 2 mg Low vaporization efficiency, low oil consumption, but extremely high concentration. Such as HQD Maxim (5%/50mg), Yuleke, IQOS, etc.
Oil-injectable Devices (Low Power) 18mg/mL - 36mg/mL of regular nicotine or 30-60mg/mL of nicotine salts. Approximately 0.5 - 3 mg Simulates smoking sensation, less oil consumption, and meets needs through high concentration.
Oil-injectable Devices (High Power) 1.5mg/mL - 6mg/mL of regular nicotine. Approximately 0.2 - 1.5 mg High vaporization efficiency, high oil consumption (up to 0.2-0.5 mL per mouth), even at a low concentration, the intake amount may still be high.
?? Important Note: The Gap Between Theory and Reality
It should be emphasized that the above calculations and estimations are theoretical values. The actual amount of nicotine inhaled and absorbed into the bloodstream (bioavailability) will be affected by various factors such as device efficiency, inhalation depth and duration, and individual metabolism.